DMD pigs suffer from GI dysfunction and malnutrition
Dystrophin deficiency causes Duchenne muscular dystrophy. In our recent work published in Cell and Bioscience, we reported that a porcine model of DMD generated by CRISPR gene editing developed muscular dystrophy, cardiomyopathy and gastrointestinal tract dysfunction. Malnutrition may further exacerbate skeletal and cardiac muscle pathology. Read the article here ...