Peer-Reviewed Journal Articles

[40] Xu L#, Lau YS#, Gao Y#, Li H, Han R*. (2019) Life-long AAV-mediated CRISPR genome editing in dystrophic heart improves cardiomyopathy without causing serious lesions in mdx mice. Mol Ther 27: 1407-1414. Full Text

[39] Lau YS, Xu L, Gao Y, Han R*. (2018) Automated muscle histopathology analysis using CellProfiler. Skelet Muscle 8: 32. Full Text

[38] Sui T, Xu L, Lau YS, Liu D, Liu T, Gao Y, Lai L*, Han R*, Li Z*. (2018) Development of muscular dystrophy in a rabbit model with Ano5 mutations generated by CRISPR/Cas9. Cell Death Dis 9: 609. Full Text

[37] Xu L, Gao Y, Lau YS, Han R*. (2018) Adeno-Associated Virus-Mediated Delivery of CRISPR for Cardiac Gene Editing in Mice. J Vis Exp doi: 10.3791/57560. Full Text

[36] Sui T, Lau YS, Liu D, Liu T, Xu L, Gao Y, Lai L*, Li Z*, Han R*. (2018) A novel rabbit model of Duchenne muscular dystrophy generated by CRISPR/Cas9. Dis Model Mech 11: dmm032201. Full Text

[35] Xu J, Xu L, Lau YS, Gao Y, Moore SA, Han R*. (2018) A novel ANO5 splicing variant in a LGMD2L patient leads to production of a truncated aggregation-prone Ano5 peptide. J Pathol Clin Res 4: 135-145. Full Text

[34] El Refaey M, Xu L, Gao Y, Canan BD, Adesanya TMA, Warner SC, Akagi K, Symer DE, Mohler PJ, Ma J, Janssen PML, Han R*. (2017) In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice. Circ Res 121: 923-929. Full Text

[33] Xu L, Zhao L, Gao Y, Xu J, Han R*. (2017) Empower multiplex cell and tissue-specific CRISPR-mediated gene manipulation with self-cleaving ribozymes and tRNA. Nucleic Acids Res 45: e28. Full Text

[32] Du L, Wu J, Qian P, Xin R, Ni Y, Han R, Meng Z, Xia J. (2017) Phylogeographical Analysis Reveals Distinct Sources of HIV-1 and HCV Transmitted to Former Blood Donors in China. AIDS Res Hum Retroviruses 33: 284-289. Full Text

[31] Dumbleton J, Agarwal P, Huang H, Hogrebe N, Han R, Gooch KJ, He X. (2016) The effect of RGD peptide on 2D and miniaturized 3D culture of HEPM cells, MSCs, and ADSCs with alginate hydrogel. Cell Mol Bioeng 9: 277-288. Full Text

[30] Meng Z, Du L, Hu N, Byrd D, Amet T, Desai M, Shepherd N, Lan J, Han R, Yu Q. (2016) Antiretroviral Therapy Normalizes Autoantibody Profile of HIV Patients by Decreasing CD33+CD11b+HLA-DR+ Cells: A Cross-Sectional Study. Medicine (Baltimore) 95: e3285. Full Text

[29] Zhu H, Han R, Duan DD. (2016) Novel Biomarkers and Treatments of Cardiac Diseases. Biomed Res Int 2016: 1315627. Full Text

[28] Xu J, El Refaey M, Xu L, Zhao L, Gao Y, Floyd K, Karaze T, Janssen PM, Han R*. (2015) Genetic disruption of Ano5 in mice does not recapitulate human ANO5-deficient muscular dystrophy. Skelet Muscle 5: 43. Full Text

[27] Xu L, Park KH, Zhao L, Xu J, El Refaey M, Gao Y, Zhu H, Ma J, Han R*. (2015) CRISPR-mediated Genome Editing Restores Dystrophin Expression and Function in mdx Mice. Mol Ther 24: 564-569. Full Text

[26] Cheng X, Zhang X, Gao Q, Ali Samie M, Azar M, Tsang WL, Dong L, Sahoo N, Li X, Zhuo Y, Garrity AG, Wang X, Ferrer M, Dowling J, Xu L, Han R, Xu H. (2014) The intracellular Ca2+ channel MCOLN1 is required for sarcolemma repair to prevent muscular dystrophy. Nat Med 20: 1187-1192. Full Text

[25] Meng Z, Han R, Hu Y, Yuan Z, Jiang S, Zhang X, Xu J. (2014) Possible pandemic threat from new reassortment of influenza A(H7N9) virus in China. Euro Surveill 19: pii: 20699. Full Text

[24] Mariano A, Xu L, Han R*. (2014) Highly efficient genome editing via 2A-coupled co-expression of two TALEN monomers. BMC Res Notes 7: 628. Full Text

[23] Zhao P, Torcaso A, Mariano A, Xu L, Mohsin S, Zhao L, Han R*. (2014) Anoctamin 6 regulates C2C12 myoblast proliferation. PLoS One 9: e92749. Full Text

[22] Iyer SS, He Q, Janczy JR, Elliott EI, Zhong Z, Olivier AK, Sadler JJ, Knepper-Adrian V, Han R, Qiao L, Eisenbarth SC, Nauseef WM, Cassel SL, Sutterwala FS. (2013) Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation. Immunity 39: 311-323. Full Text

[21] Lin B, Govindan S, Lee K, Zhao P, Han R, Runte KE, Craig R, Palmer BM, Sadayappan S. (2013) Cardiac myosin binding protein-C plays no regulatory role in skeletal muscle structure and function. PLoS One 8: e69671. Full Text

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