Publications

Publications

[64] Han R*. (2023) First in vivo base-editing trial shows promise. Molecular Therapy doi: 10.1016/j.ymthe.2023.12.001. Full Text

[63] Li H, Wang P, Zhang C, Zuo Y, Zhou Y, Han R*. (2023) Defective BVES-mediated feedback control of cAMP in muscular dystrophy. Nature Communications 14: 1785. Full Text

[62] Zuo Y, Wang P, Gao Y, Zhang C, Zhou Y, Li H, Chen Z, Yang Z, Xu J, Zhang J, Chen YE, Han R*. (2022) A self-inactivating system for AAV-mediated in vivo base editing. biorxiv doi: 10.21203/rs.3.rs-1663604/v1. Full Text

[61] Koike T, Koike Y, Guo Y, Yang D, Song J, Xu J, Zhao X, Zhu T, Li R, Wen B, Sun D, Rom O, Han R, Fan J, Garcia-Barrio MT, Zhang J, Chen YE. (2022) IDOL deficiency inhibits cholesterol-rich diet-induced atherosclerosis in rabbits. biorxiv doi: 10.1101/2022.05.03.490218. Full Text

[60] Zuo Y, Zhang C, Zhou Y, Li H, Xiao W, Herzog RW, Xu J, Zhang J, Chen EY, Han R*. (2023) Liver-specific in vivo base editing of Angptl3 via AAV delivery efficiently lowers blood lipid levels in mice. Cell & Bioscience 13: 109. Full Text

[59] Wang P, Li H, Zhu M, Han RY, Guo S, Han R*. (2022) Correction of DMD in human iPSC-derived cardiomyocytes by base editing-induced exon skipping. Molecular Therapy - Methods & Clinical Development 28: 40-50. Full Text

[58] Li H, Wang P, Hsu E, Pinckard KM, Stanford KI and Han R*. (2022) Systemic AAV9.BVES Delivery Ameliorates Muscular Dystrophy in a Mouse Model of LGMDR25. Molecular Therapy doi: 10.1016/j.ymthe.2022.11.012. Full Text

[57] Zou X, Ouyang H, Lin F, Zhang H, Yang Y, Pang D, Han R*, Tang X*. (2022) MYBPC3 deficiency in cardiac fibroblasts drives their activation and contributes to fibrosis. Cell Death & Disease doi: 10.1038/s41419-022-05403-6. Full Text

[56] Li H, Zhang L, Zhang L and Han R*. (2022) Autophagy in striated muscle diseases Frontiers in Cardiovascular Medicine doi: 10.3389/fcvm.2022.1000067. Full Text

[55] Zhang M, Urabe G, Ozer HG, Xie X, Webb A, Shirasu T, Li J, Han R, Kent KC, Wang B and Guo LW. (2022) Angioplasty induces epigenomic remodeling in injured arteries. Life Science Alliance 5: e202101114. Full Text

[54] Li H, Xu L, Gao Y, Zuo Y, Yang Z, Zhao L, Chen Z, Guo J, Han R*. (2021) BVES Is a Novel Interactor of ANO5 and Regulates Myoblast Differentiation. Cell & Bioscience 11(1): 222. Full Text

[53] Li H, Lin P-H, Pranav G, Li X, Zhao L, Zhou X, Li Z, Wei S, Xu L, Han R, Lu J, Tan T, Yang D-H, Chen Z-S, Pawlik TM, Merritt RE, Ma J (2021) MG53 suppresses tumor progression and stress granule formation by modulating G3BP2 activity in non-small cell lung cancer. Molecular Cancer 20: 118. Full Text

[52] Zou X, Ouyang H, Pang D, Han R* and Tang X*. (2021) Pathological alterations in the gastrointestinal tract of a porcine model of DMD. Cell & Bioscience 11(1): 131. Full Text

[51] Xu L, Zhang C, Li H, Wang P, Gao Y, Mokadam NA, Ma J, Arnold WD, Han R*. (2021) Efficient precise in vivo base editing in adult dystrophic mice. Nature Communications 12(1): 3719. Full Text

[50] Yang D, Liang X, Pallas B, Hoenerhoff M, Ren Z, Han R, Zhang J, Chen YE, Jin J-P, Sun F, Xu J. (2021) Production of CFTR-deltaF508 Rabbits Frontiers in Genetics 11: 627666. Full Text

[49] Xu J, Zhang J, Yang D, Song J, Pallas B, Zhang C, Hu J, Peng X, Christensen N, Han R* and Chen YE*. (2021) Gene editing in rabbits: unique opportunities for translational biomedical research. Frontiers in Genetics 12: 642444. Full Text

[48] Li H, Zhao L, Lau YS, Zhang C, Han R*. (2020) Genome-wide CRISPR screen identifies LGALS2 as an oxidative stress-responsive gene with an inhibitory function on colon tumor growth. Oncogene doi: 10.1038/s41388-020-01523-5. Full Text

[47] Lau YS, Zhao L, Zhang C, Li H, Han R*. (2020) Genetic disruption of the inflammasome adaptor ASC has minimal impact on the pathogenesis of Duchenne muscular dystrophy in mdx Mice. Life Sciences 257: 118069. Full Text

[46] Sui T, Xu L, Lau YS, Liu D, Liu T, Gao Y, Lai L, Han R, Li Z. (2020) Correction: Development of muscular dystrophy in a CRISPR-engineered mutant rabbit model with frame-disrupting ANO5 mutations. Cell Death Dis doi: 10.1038/s41419-020-2659-x: . Full Text

[45] Dwivedi P, Kiran S, Han S, Dwivedi M, Khatik R, Fan R,Mangrio F, Du K, Zhu Z, Yang C, Huang F, Ejaz A, Han R, Si T, Xu R. (2020) Magnetic targeting and ultrasound activation of liposome-microbubble conjugate for enhanced delivery of anti-cancer therapies. ACS Applied Materials & Interfaces 12(21): 23737-23751. Full Text

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