Peer-Reviewed Journal Articles

[20] Xu L, Zhao P, Mariano A, Han R*. (2013) Targeted Myostatin Gene Editing in Multiple Mammalian Species Directed by a Single Pair of TALE Nucleases. Mol Ther Nucleic Acids 2: e112. Full Text

[19] Mariano A, Henning A, Han R*. (2013) Dysferlin-deficient muscular dystrophy and innate immune activation. FEBS J 280: 4165-4176. Full Text

[18] Zhong Z, Zhai Y, Liang S, Mori Y, Han R, Sutterwala FS, Qiao L. (2013) TRPM2 links oxidative stress to NLRP3 inflammasome activation. Nat Commun 4: 1611. Full Text

[17] Wu J, Meng Z, Xu J, Lei Y, Jin L, Zhong P, Han R, Su B. (2013) New emerging recombinant HIV-1 strains and close transmission linkage of HIV-1 strains in the Chinese MSM population indicate a new epidemic risk. PLoS One 8: e54322. Full Text

[16] Han R, Rader EP, Levy JR, Bansal D, Campbell KP. (2011) Dystrophin deficiency exacerbates skeletal muscle pathology in dysferlin-null mice. Skelet Muscle 1: 35. Full Text

[15] Xu L, Pallikkuth S, Hou Z, Mignery GA, Robia SL, Han R*. (2011) Dysferlin forms a dimer mediated by the C2 domains and the transmembrane domain in vitro and in living cells. PLoS One 6: e27884. Full Text

[14] Han R, Kobuke K, Anderson M, Beltran-Valero de Bernabe D, Kobayashi Y, Yang B, Campbell KP. (2011) Improved genotyping of the dysferlin-null mouse. Protocol Exchange doi: 10.1038/protex.2011.232.. Full Text

[13] Zhao P, Xu L, Ait-Mou Y, de Tombe PP, Han R*. (2011) Equal force recovery in dysferlin-deficient and wild-type muscles following saponin exposure. J Biomed Biotechnol 2011: 235216. Full Text

[12] Han R*. (2011) Muscle membrane repair and inflammatory attack in dysferlinopathy. Skelet Muscle 1: 10. Full Text

[11] Han R, Frett EM, Levy JR, Rader EP, Lueck JD, Bansal D, Moore SA, Ng R, Beltran-Valero de Bernabe D, Faulkner JA, Campbell KP. (2010) Genetic ablation of complement C3 attenuates muscle pathology in dysferlin-deficient mice. J Clin Invest 120: 4366-4374. Full Text

[10] Han R, Kanagawa M, Yoshida-Moriguchi T, Rader EP, Ng RA, Michele DE, Muirhead DE, Kunz S, Moore SA, Iannaccone ST, Miyake K, McNeil PL, Mayer U, Oldstone MB, Faulkner JA, Campbell KP. (2009) Basal lamina strengthens cell membrane integrity via the laminin G domain-binding motif of alpha-dystroglycan. PNAS 106: 12573-12579. Full Text

[9] Han R, Campbell KP. (2007) Dysferlin and muscle membrane repair. Curr Opin Cell Biol 19: 409-416. Full Text

[8] Han R, Bansal D, Miyake K, Muniz VP, Weiss RM, McNeil PL, Campbell KP. (2007) Dysferlin-mediated membrane repair protects the heart from stress-induced left ventricular injury. J Clin Invest 117: 1805-1813. Full Text

[7] Han R, Grounds MD, Bakker AJ. (2006) Measurement of sub-membrane [Ca2+] in adult myofibers and cytosolic [Ca2+] in myotubes from normal and mdx mice using the Ca2+ indicator FFP-18. Cell Calcium 40: 299-307. Full Text

[6] Kirilak Y, Pavlos NJ, Willers CR, Han R, Feng H, Xu J, Asokananthan N, Stewart GA, Henry P, Wood D, Zheng MH. (2006) Fibrin sealant promotes migration and proliferation of human articular chondrocytes: possible involvement of thrombin and protease-activated receptors. Int J Mol Med 17: 551-558. Full Text

[5] Han R, Bakker AJ. (2006) The effect of the PKC inhibitor calphostin C and the PKC agonist phorbol 12-myristate 13-acetate on regulation of cytosolic Ca2+ in mammalian skeletal muscle cells. Toxicol Appl Pharmacol 212: 247-255. Full Text

[4] Yip KH, Zheng MH, Steer JH, Giardina TM, Han R, Lo SZ, Bakker AJ, Cassady AI, Joyce DA, Xu J. (2005) Thapsigargin modulates osteoclastogenesis through the regulation of RANKL-induced signaling pathways and reactive oxygen species production. J Bone Miner Res 20: 1462-1471. Full Text

[3] Xu J, Wang C, Han R, Pavlos N, Phan T, Steer JH, Bakker AJ, Joyce DA, Zheng MH. (2005) Evidence of reciprocal regulation between the high extracellular calcium and RANKL signal transduction pathways in RAW cell derived osteoclasts. J Cell Physiol 202: 554-562. Full Text

[2] Han R, Suizu T, Grounds MD, Bakker AJ. (2003) Effect of indomethacin on force responses and sarcoplasmic reticulum function in skinned skeletal muscle fibers and cytosolic [Ca2+] in myotubes. Am J Physiol Cell Physiol 285: C881-890. Full Text

[1] Han R, Bakker AJ. (2003) The effect of chelerythrine on depolarization-induced force responses in skinned fast skeletal muscle fibres of the rat. Br J Pharmacol 138: 417-426. Full Text

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